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Medication Table: ADHD Medications

Summary: This medication table is for informational purposes only and is not a replacement for clinical judgment and consulting a drug reference (such as PDR or Lexi-Comp).
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ADHD Medications

Stimulants

Medication

Forms

Dose (Start, Initial Target, Max)

Long-acting



Methylphenidate OROS (Concerta)

Extended release tab 18,27,36,54 mg

Child: Start 18 mg q AM, increase by 9-18 mg weekly, max 72 mg daily (or 1 mg/kg/day)

Adolescent/ Adult: Start 36 mg q AM, increase by 9-18 mg weekly, max 90 mg qAM

Adderall XR (amphetamine mixed salt)

Caps 5,10,15,20,25,30 mg

Child: Start 5-10 mg q AM, increase by 5 mg weekly, max 30 mg qAM

Adolescents/Adult: Start 5-10 mg q AM, increase by 5 mg weekly, max 50 mg qAM

Dexedrine spansule

Cap 10,15 mg

Child: Start 10 mg q AM, increase by 2.5-5 mg weekly, max 20-30 mg qAM

Adult: Max 50 mg daily

Vyvanse®

(lisdexamfetamine dimesylate)


Cap 10,20,30,40, 50,60,70 mg

Child: Start 20 mg qAM, titrate up 10 mg weekly, max 60 mg qAM

Adolescent: Start 30 mg qAM, titrate 10 mg weekly, max 70 mg qAM

Adult: Start 30 mg daily, increase by 10 mg weekly, max 70 mg q AM

Methylphenidate (Biphentin)

Cap 10,15,20,30,40,50,60,80 mg

Child: Start 10 mg qAM, titrate up by 5-10 mg weekly, max 60 mg qAM

Adolescent: Start 20 mg qAM, titrate up by 5-10 mg weekly, max 80 mg qAM

Short-acting



Dexedrine®

(dextro-amphetamine sulphate)


5mg tab

Child/youth: Start 2.5 - 5mg bid, increase 2.5-5 mg weekly, max 20-30 mg qAM

Adult: Max 50 mg daily


Methylphenidate (Ritalin)

Tab 5,10,20 mg

Child: Start 2.5 mg bid-tid, increase 5 mg weekly, max 60 mg qAM

Adult: Start 2.5 mg bid-qid; increase by 5 mg weekly; max 100 mg daily

Stopping Stimulant Medications

Stimulant medications can usually be stopped suddenly without needing to taper down.

Non-Stimulants

Medication

Forms

Dose (Start, Initial Target, Max)

Alpha adrenergic



Clonidine (Catapres)


Child: Start 0.05mg nightly, max 0.35 mg daily in divided doses.

Guanfacine XR (Intuniv)

Tab XR: 1, 2, 3, 4 mg

As monotherapy

Child: Initially 0.5-1 mg at bedtime titrated to maximum

dosage of 3 mg qhs or divided doses

Adolescent: Up to 7 mg qhs or divided doses


As adjunctive therapy

Child/Adolescent: 4 mg max

Others



Atomoxetine (Strattera)

Cap 10, 18, 25, 40, 60, 80,100 mg

Child: Start 0.5 mg/kg/day, titrate up to 0.8 mg/kg/day initial therapeutic target; max 1.2 mg/kg/day

Adolescent: Start 0.5 mg/kg/day; titrate up to 60 mg/day then 80 mg/day

Max dose lesser of 1.4 mg/kg/day or 100 mg daily

Adult: Start 40 mg daily x 1-2 weeks; then titrate up to 60-80 mg q AM

Max lesser of 1.4 mg/kg/day or 100 mg

Bupropion SR

(Wellbutrin SR)


Tab: 100, 150 mg ;

Do not crush/ cut/ chew

Child: Unknown

Adol/adult: Start 100 mg, initial target 150 mg daily; max 400 mg daily

Bupropion XL (Wellbutrin XL)

Tab: 150, 300 mg ;

do not crush/cut/chew

Child: Unknown

Adol/adult: Start 150 mg, initial target 300 mg; max 450 mg





* Disclaimer: This medication table is a rough summary only and is not a replacement for clinical judgment and consulting a drug reference such as PDR or Lexi-Comp.

Stopping Non-Stimulants

Alpha adrenergics such as clonidine or guanfacine should be stopped gradually over 2-4 weeks, in order to avoid any rebound hypertension.

Atomoxetine, bupropion are long acting and have antidepressant effects, and should also be tapered gradually and then stopped over 4-weeks.

Date Posted: Oct 20, 2020
Date of Last Revision: Oct 20, 2020

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